Phylogeny derived from homodimeric endonuclease correlates with its pre-RNA substrates

Mitra, Sanga and Das, Smarajit and Sahoo, Satyabrata and Sinha, Chandana and Chakrabarti, Jayprokas (2011) Phylogeny derived from homodimeric endonuclease correlates with its pre-RNA substrates. Advances in Bioscience and Biotechnology, 02 (03). pp. 117-122. ISSN 2156-8456

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Abstract

Amongst endonuclease, the homodimeric variety is found in many prokaryotes for processing of the introns out from pre-RNAs. But as the variety and the complexity of introns rise with evolution, do the homodimeric endonuclease adapt to the changes? The correlations between evolving pre-RNAs and adapting homodimeric endonuclease in lower prokaryotes is investigated in this paper. First, we construct and observe the appearance of a long branch in the phylogeny based on homodimeric endonuclease. To appreciate the finer aspects of accelerating evolution near this long branch, we delve deeper into the pre-RNA substrates of the endonuclease. Computational evidence of an as-yet-unreported noncoding RNA gene then emerges from this study. The capabilities of homodimeric endonuclease and the complexities of its pre-RNA substrates appear to evolve in steps together.

Item Type: Article
Subjects: Archive Science > Biological Science
Depositing User: Managing Editor
Date Deposited: 23 Mar 2023 08:53
Last Modified: 07 Sep 2024 10:49
URI: http://editor.pacificarchive.com/id/eprint/438

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