Compressive Review on Plant Profile, Ethnomedicinal Uses, Phytochemistry and Pharmacology of Paeonia emodi Royle (Himalayan Paeony)

Members of the genus Paeonia, which contains well-known ornamentals as well as traditional medicinal plants with a history reaching back over 1500 years, may be found all throughout the Northern Hemisphere. Many of these ethnomedicinal properties have been studied in animal models. It has been listed as a critically endangered plant species. P. emodi has been shown to have antioxidant, nephroprotective, lipoxygenase inhibitory, cognition and oxidative stress release, cytotoxic, anti-inflammatory, antiepileptic, anticonvulsant, haemaglutination, alphachymotrypsin inhibitory, hepatoprotective, hepatic chromes, and pharmacokinetics of carbamazepine expression. spas Data was acquired from unpublished theses (India, China, Pakistan, and Nepal) and numerous published research articles related to pharmacology, phytochemistry, and other activities using certain keywords. The pertinent information about medicinal uses, taxonomic/common names, parts used, collection and recognition source, authentication, voucher specimen number, plant extracts and their characterization, isolation and characterization of phytochemicals, methods of study (in silico, in vivo, or in vitro), model organism used, dose and time, minimal active concentration, bioactive compound(s), mechanism of action on single or multiple targets, and toxicological information. Triterpenoids, monoterpenoids, phenolics, and tannins are among the natural substances produced by the species. The purpose of this study was to collect broad traditional medicinal uses, phytochemistry, pharmacology, and toxicological data on P. emodi. This work also emphasises taxonomic validity, experimental design quality, and weaknesses in previously published Himalayan paeony material, which may help researchers plan for future research.