Antioxidant, Cytotoxic and larvicidal Potential in Oxalis latifolia Kunth. Methanolic Leaf Extract

Krishnan, R. Gopi and Murugesh, S. (2021) Antioxidant, Cytotoxic and larvicidal Potential in Oxalis latifolia Kunth. Methanolic Leaf Extract. Journal of Pharmaceutical Research International, 33 (46A). pp. 269-275. ISSN 2456-9119

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Official URL: https://doi.org/10.9734/jpri/2021/v33i46A32866

Abstract

Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract.

Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquefasciatus (IVth instar) larvae was used for larvicidal test.

Results: Antioxidant and cytotoxicity exhibits significant activities with IC50 value of 442.94 µg/mL and also the cytotoxicity activity IC50 values of 50.00μg/mL for HT-29. Larval mortality against the larvae of Cx. quinquefasciatus showed best activity with LC50 09.50mg/L and LC90 28.72 mg/L.

Conclusion: Thus, this study proved that methanolic leaf extracts of O. latifolia have significant biological activities. Hence, it can be used for pharmacetutical applications.

Item Type:	Article
Subjects:	Archive Science > Medical Science
Depositing User:	Managing Editor
Date Deposited:	20 Feb 2023 10:27
Last Modified:	25 Apr 2024 09:25
URI:	http://editor.pacificarchive.com/id/eprint/11

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